Thursday, December 29, 2011

Wizards Vs. Hawks Final Score: Atlanta Wins Second Straight 101-83 Over Washington

The Atlanta Hawks weren't nearly as dominant as their Tuesday night victory but they were good enough to hand the Washington Wizards a 101-83 loss in their home opener at Philips Arena. Atlanta started the game with an 11-0 run and has an answer for every Washington run in the game.

After the game, Larry Drew wasn't as pleased with the Hawks effort citing that they didn't seem as locked in at both ends of the floor. Washington successfully cut a big Hawks lead down to 13 points in the fourth quarter before Atlanta woke up enough to stretch it back out.

Joe Johnson led the way for the Hawks with 18 points and four assists. Marvin Williams had his second straight good game finishing with 17 points and eight rebounds. Both Josh Smith and Al Horford logged double-doubles while Jeff Teague finished with 11 points and five assists. Atlanta hit 43 percent of their field goal attempts and went inside for 36 points in the paint. The intent on getting the ball inside paid off with Atlanta going 28-35 at the free throw line.

Nick Young led the Wizards with 21 points and John Wall finished with 20 points and six assists. JaVale McGee finished with a double-double 15 points and 12 rebounds but Andray Blatche was a non-factor finishing with four points on 2-13 shooting.

For more on this game, Hawks fans should check out Peachtree Hoops and Wizards fans should visit Bullets Forever. For everything NBA basketball check out SB Nation's NBA hub.

Source: http://atlanta.sbnation.com/atlanta-hawks/2011/12/28/2667386/wizards-vs-hawks-final-score-2011

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Wednesday, December 28, 2011

No iPad Mini in 2012?

There has been a great clamor from consumers for Apple to release an iPad mini or a 7-inch tablet but just like Steve Jobs' said in a statement, small iPad will not be added in their product line in the near future. However, we may see a cheaper iPad 2 next year.

Contrary to rumors going around, Apple will not release a smaller iPad. There are various reasons on why this will happen. However, one of the reasons is former Apple owner Steve Jobs' statement towards the miniature device. "One naturally thinks that a 7-inch screen would offer 70 per cent of the benefits of a 10-inch screen," Jobs said during a 2010 earnings call. "Unfortunately, this is far from the truth. ... The reason we [won't] make a 7-inch tablet isn't because we don't want to hit [a lower] price point, it's because we think the screen is too small to express the software. As a software driven company, we think about the software strategies first."

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There are rumors that Apple is testing the device but the company will not be releasing its version next year. Part of the appeal of a smaller tablet is the price point. Smaller tablets are usually priced in the mid-level price range, below $400. Blair thinks Apple will use a different strategy to hit that tier:

"We believe Apple is highly likely to keep the iPad 2 on the production line after the launch of iPad 3 and offer it at a lower price point in an effort to address demand at the mid-tier, what we view as the $249 to $499 range. We believe iPad 2?s price could drop to the $349 to $399 range with Apple offering a single 16GB model."

It is expected that the price of the iPad 2 will be lower since a next generation of tablet is expected to be introduced next year. According to the Taiwanese news agency DigiTimes, tech giant Apple, Inc. will be releasing its much-awaited next generation of iPad in the next three to four months.

DigiTimes reported that their sources from the Apple's supply chain said that the production for the iPad 3 ramped up and the production of current generation of iPad decreased. Specifically, the source of the news agency confirmed that OEM production of the iPad 2 will remain high, producing 14 to 15 million units by the fourth quarter of 2011 but will drastically decline to 4 to 5 million units on the first quarter of 2012 to pave the way for the new iPad.?

Source: http://www.ibtimes.com/articles/273374/20111228/ipad-mini-2012.htm

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Biochemical role of the collagen-rich tumour microenvironment in pancreatic cancer progression.

Source

*Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, U.S.A.

Abstract

PDAC (pancreatic ductal adenocarcinoma) is among the most deadly of human malignances. A hallmark of the disease is a pronounced collagen-rich fibrotic extracellular matrix known as the desmoplastic reaction. Intriguingly, it is precisely these areas of fibrosis in which human PDAC tumours demonstrate increased expression of a key collagenase, MT1-MMP [membrane-type 1 MMP (matrix metalloproteinase); also known as MMP-14]. Furthermore, a cytokine known to mediate fibrosis in vivo, TGF-?1 (transforming growth factor-?1), is up-regulated in human PDAC tumours and can promote MT1-MMP expression. In the present review, we examine the regulation of PDAC progression through the interplay between type?I collagen (the most common extracellular matrix present in human PDAC tumours), MT1-MMP and TGF-?1. Specifically, we examine the way in which signalling events through these pathways mediates invasion, regulates microRNAs and contributes to chemoresistance.

Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=22187935&dopt=Abstract

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Tuesday, December 27, 2011

London subway strike delays Boxing Day shoppers (AP)

LONDON ? London's subway drivers walked out over a pay dispute Monday, causing trouble for thousands of shoppers out to take advantage of traditional Boxing Day sales.

Transport for London warned that shoppers seeking bargains in the capital's shopping centers face "significant disruption." Several subway lines have been suspended, and limited services are operating on the rest of the network.

The ASLEF union is staging the one-day strike to demand extra pay as well as a day off for members working on the public holiday.

The London Underground ? the organization that manages the subway system ? condemned the move, saying it was pointless and demonstrated "a complete disregard for our customers." Authorities said extra buses are running in the main shopping areas to cater to the increased flow of travelers on one of the year's busiest shopping days.

Despite the disruptions, large crowds of shoppers ? some lining up from midnight ? started flooding department stores in London and other British cities as soon as doors opened early Monday.

Selfridges, one of Britain's most popular department stores, reported its biggest ever first hour of trading Monday morning.

In northwest London, the Brent Cross shopping center said that 10,000 people had piled through its doors within an hour of opening.

The ASLEF union plans to stage three more strikes in January and February if the dispute is not resolved.

Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/ap/20111226/ap_on_re_eu/eu_britain_subway_strike

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For refugees, leaving California a gamble

OAKLAND -- The rumors circulated for months: Pennsylvania is a better place to live than Oakland for newly arrived Bhutanese refugees.

"All the Bhutanese are migrating to Pennsylvania," Benu Mainali said. "They say it's better. It's easier to find a job."

The 29-year-old refugee wasn't sure whether he should believe the stories of greener Pennsylvanian pastures. He also knew they would soon be covered in snow. But after 19 months in California, he and his family packed their bags 10 days ago, moved across the country and took a gamble on the unknown.

A family that fled rural Bhutan and spent 18 years in a cramped U.N. refugee camp had grown comfortable in Oakland. Now, restless hopes and family ties have uprooted them again.

As he vacuumed his emptied East Oakland apartment and his wife scrubbed the kitchen on their last night in the Bay Area, the couple knew they risked everything they had gained in their short time in the United States.

"I am leaving this place, my apartment, my work," Benu Mainali said. "I have to go start from the beginning. I might regret this later, leaving California, but all my family members are there (in the Northeast). I have to go."

Secondary migration

The Mainalis are following a pattern some call "secondary migration," a state-to-state movement as old as the nation itself.

It's how Scandinavian homesteaders

populated the upper Midwest and Portuguese came to farm the Central Valley, how Long Beach became a Cambodian hub and Pittsburgh, Pa., is turning into a Bhutanese one.

Since early 2008, the State Department and community organizations around the country have welcomed nearly 50,000 Bhutanese exiles. The Nepali-speaking refugees spent decades in crowded camps in eastern Nepal after fleeing ethnic conflict in southern Bhutan. International organizations sought to disperse them across the developed world, from Alaska to Australia's Tasmania, trying not to burden any one place with too many people at once.

Now, the newcomers are sorting out where they really want to live.

Oakland remains one of the top 20 cities for Bhutanese refugees in the United States, but among the hundreds who have moved to the city and neighboring Alameda in the past four years, some are already trying their luck elsewhere.

The national Office of Refugee Resettlement does not track secondary migration, but every Bhutanese family knows another that took off for another state this year or is making plans for 2012.

Several families moved from Oakland to upstate New York in recent months, including Benu Mainali's brother and parents. Another migrated to the eastern North Dakota cities of Fargo and Grand Forks. Economic factors drive some of the movement -- North Dakota's cities have the lowest unemployment rates in the nation.

Family reunification may be the biggest tug. One extended family disperses around the country, then relatives share stories about which location offers the best opportunities. For the Mainalis, the spot was the Great Lakes corridor.

They were not alone: In recent months, Pennsylvania surpassed Texas as the top destination for Bhutanese refugees, and upstate New York is not far behind, according to data from the International Organization for Migration, the group tasked to resettle them.

The Mainalis' journey

This newspaper began following the Mainalis in spring 2010, meeting them at the tiny bamboo hut in southeastern Nepal where they had been living since 1992.

Weeks before they set off for America, Benu Mainali, his newlywed wife, Leela, and his 60-something parents informed workers at the United Nations-run camp that they wanted to migrate to Oakland because two relatives had moved there several months earlier.

They had seen photographs of the Golden Gate Bridge but knew almost nothing about California. A former teacher at the camp where he grew up, Benu Mainali was eager to learn and quickly found in Oakland what he desired: A steady job, new and old friends, good weather, freedom and a better quality of life.

He started at $8 an hour stocking goods at Farmer Joe's, a gourmet grocery in the Oakland foothills, and rose to assistant manager at $10 an hour. Supervisors were impressed by his diligence, confidence and his English skills.

Leela Mainali, 21, found work at a pizza shop before giving birth to the couple's first child this summer. Benu's parents, Bishnu and Devi, -- were one-time farmers who spoke no English but were the glue that kept the family together and helped care for their grandchildren.

The apartment the family shared in Oakland's Laurel district became a social space for visitors. Up until his last week there, Benu Mainali used it for meetings of BCA Productions, or Bhutanese California Artist Productions, a filmmaking club for fellow exiles.

Despite the language barriers, 63-year-old Bishnu Mainali, with her warm and expressive personality, also made fast friends. Her neighbor Paw Boh, a Karen refugee from Myanmar,? would visit daily and sometimes take her elder friend to the farmer's market. They communicated in a universal language of gestures and smiles.

Thoughts of moving

Leela Mainali was the first to broach the idea of leaving Oakland, whispering the names of eastern cities in nighttime conversations with her husband. She heard the stories of roomier, less expensive apartments, more plentiful work and less crime. She missed her relatives who were moving to the East Coast. Her older sister's family landed in northern Florida but could not find work there, so they moved to Pittsburgh this fall and found employment immediately despite their limited English.

"In Pennsylvania, it makes no difference," Benu Mainali said. "Even the people who don't speak a word, they're getting a job and making good money."

Benu Mainali's youngest brother, Yadhu, was the first to arrive in Oakland and the first to leave. He took off to join the brothers' oldest siblings in Buffalo, N.Y., where he quickly found a job, started a vocational program and convinced the rest of the family to join him. He wanted their support and company.

Benu Mainali was reluctant. He wanted to quit his job eventually and learn radiology, but he could do that in California, where he already had a network of support.

"I tried to convince them to stay with me here and call Yadhu also to come back," he said. His mother, however, thought her youngest son needed her help. She spent two weeks trying to convince her husband they should leave, and he finally agreed.

"I want to go to New York, just to help him a little bit, so he can go to school," she said, speaking in Nepali through an interpreter. "California is much better to live in, but then I heard the words my son had spoken. The decision is maybe the wrong decision, but because of love for my son, I am leaving."

Dozens of people came to bid the older couple farewell as they packed for New York, and Bishnu Mainali was visibly saddened.

"I am nervous right now, not because of the trip, but because I will be leaving my granddaughter," she said.

The Nov. 30 flight was stressful. Clad in winter clothes, Bishnu and Devi Mainali landed in Denver and were supposed to pick up a connecting flight but thought they were already in Buffalo so walked out of the airport. They wondered why the family wasn't there to pick them up. Bishnu Mainali used hand signals to ask a man with a cellphone for help. They returned to the terminal in time to catch their next flight.

Optimism prevails

By the time his parents had left, Benu Mainali had changed his mind and was ready to leave. Being in the same region as his parents made the move more palatable. At first, the couple and their child would live with his wife's family in a Pittsburgh suburb, about a four-hour drive from Buffalo.

Still, friends persuaded him not to go. Neighbor and family friend Anil Verma, a Myanmar refugee, told the Mainalis it was a bad idea.

"They hear that everything's better. But in reality, it's not," Verma said. "Don't go based on what other people are saying. Wherever you want to try your luck, you go. But don't rely on anyone. Sometimes, things do not come true."

Jobs may be more available in the Rust Belt and Midwest than in the Bay Area, but they pay lower wages, Verma told them. Rents are lower, but fresh vegetables and utility bills can cost more. Oakland is diverse and welcoming, but other cities may be less so and have fewer social services. And moving costs money.

The younger Mainalis stuffed their belongings -- clothes, a pressure cooker and some other kitchen equipment -- in the trunk of their Toyota and had the car towed to Pittsburgh for $850. They spent hundreds more on airfare and have about $5,000 left in savings.

They have car payments and are paying back the International Organization for Migration in monthly installments for the flight that brought them to the United States.

If jobs are hard to find, they could be in financial trouble. But the frugal, plucky family has been through much worse and remains optimistic.

Pittsburgh "may be better than here," Leela Mainali said hours before she left Oakland on Dec. 15.

"After five or six years, after completing school, it may be a better life than now. I will start work, and Benu can study. Or maybe after five years, we will be back in California."

Bhutanese-American hubs
Five years ago, most U.S. cities had just a handful of people who identified as Bhutanese or none at all. Beginning in 2008, a mass resettlement of nearly 50,000 Nepali-speaking refugees from Bhutan has dispersed them across dozens of American cities. The list below charts the 20 metro areas with the largest Bhutanese population as of April 2010, when the U.S. Census was taken. Thousands more have migrated to the United States since the census, while others have moved from one U.S. city to another looking for better opportunities.
Atlanta: 1,693
Dallas-Fort Worth: 993
Houston: 792
Seattle: 733
Phoenix: 639
Tucson, Ariz.: 571
Denver: 566
Syracuse, N.Y.: 523
Chicago: 513
New York City: 498
Nashville, Tenn.: 462
Rochester, N.Y.: 411
Salt Lake City: 399
Erie, Pa.: 395
Akron, Ohio: 388
Oakland: 376
Buffalo, N.Y.: 370
Manchester, N.H.: 320
St. Louis: 307
Concord, N.H.: 291
Source: U.S. Census 2010

Source: http://www.insidebayarea.com/news/ci_19616162?source=rss

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Monday, December 26, 2011

Researchers Present Findings From Kentucky Breast Cancer Patients With Disease Relapse

Printed From BioPortfolio.com

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{Medical News Today via BioPortfolio} The University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team presented findings from their studies on relapse of breast cancer at the San Antonio Breast Cancer Symposium this month. The two studies aimed to characterize further risk factors for presentation with metastatic disease or risk of early metastatic relapse after initial therapy. Data for each study was collected from 1,089 patients at the UK Markey Cancer Center between January 2007 and May 2011...

Original Article: Researchers Present Findings From Kentucky Breast Cancer Patients With Disease Relapse

Medical News Today

  • Breast Cancer

    Breast cancer in the UK is diagnosed in nearly? 46,000 people? each year, with just over 12,000 dying from breast cancer each year in he UK. There are several risk factors for developing b...

  • Tumor markers

    Tumor markers are substances produced by tumor cells or by other cells of the body in response to cancer or certain benign (noncancerous) conditions. These substances can be found in the blood, in t...

  • Epithelial cell adhesion molecule EpCAM CD326

    Epithelial cell adhesion molecule (EpCAM; CD326) is a cell surface protein that is frequently expressed at high level on most solid tumor types, including prostate, breast, colon, gastric, ovarian,...

  • Selective Estrogen Receptor Modulators SERMs

    Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ER) agonists or antagonist depending on the targeted tissue and the specific configuration of the used SERM. Effects on bone, e...

  • Cervical Cancer

    Cervical cancer is a malignant neoplasm of the cervix uteri or cervical area. Symptoms include vaginal bleeding, but may not present until later stages of the cancer. Cervical cancer can be treated...

  • Breast Lumps
  • Select eye findings in conjunctival disorders
  • Cancer

    Cancer (malignant neoplasm) is a class of disease. There are malignancy properties that cancer cells have;? 1. The diseased tissue grows uncontrollably, ignoring growth arrest signals,?...

  • Antibody Drug Conjugates ADC

    The humanized anti-Her2 monoclonal antibody Herceptin (trastuzumab) has become the mainstay in the treatment of Her2-positive breast cancer. Combining trastuzumab with the potent cytotoxic DM1 via a s...

  • Mastalgia Breast Pain

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Source: http://c.moreover.com/click/here.pl?r5660151107&f=378

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Source: http://www.dealextreme.com/p/8500mah-rechargeable-external-battery-back-case-for-ipad-2-black-109640

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