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Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/vmmcjZKSVsg/story01.htm
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Friday, January 20, 2012
Apple posts iBooks Author instructional video
Following up on the education event in New York, Apple has posted an instructional video for the new iBooks Author app available in the Mac App Store. The video goes
Suspect in taped Winter Classic fight posts bail
This undated photo provided by the Philadelphia Police Department shows Dennis Veteri. Veteri, who police say was the instigator of a brutal fight that ended with a New York Rangers fan lying stunned in the middle of a Philadelphia intersection, faces assault charges stemming from the altercation between rival fans following the NHL Winter Classic hockey game. Veteri was charged Thursday Jan. 12, 2012, with aggravated and simple assault and other counts stemming from the Jan. 2 fight following the outdoor matchup between the Rangers and Philadelphia Flyers. (AP Photo/Philadelphia Police Department)
This undated photo provided by the Philadelphia Police Department shows Dennis Veteri. Veteri, who police say was the instigator of a brutal fight that ended with a New York Rangers fan lying stunned in the middle of a Philadelphia intersection, faces assault charges stemming from the altercation between rival fans following the NHL Winter Classic hockey game. Veteri was charged Thursday Jan. 12, 2012, with aggravated and simple assault and other counts stemming from the Jan. 2 fight following the outdoor matchup between the Rangers and Philadelphia Flyers. (AP Photo/Philadelphia Police Department)
PHILADELPHIA (AP) ? The New Jersey man has posted bail stemming from charges over a street fight that left another hockey fan unconscious outside a Philadelphia cheesesteak shop following the NHL Winter Classic.
Online court records say Dennis Veteri was released Wednesday after 10 percent of the $400,000 bail was posted. A judge had raised bail from $100,000 earlier in the day.
Video of the Jan. 2 fight posted online shows a confrontation between Philadelphia Flyers fans and New York Rangers fans escalating into a brawl that ends with a man motionless on the ground.
Police say Veteri was the aggressor and landed the punch that knocked out Woodbridge Township, N.J., police officer and Iraq war veteran Neal Auricchio.
Veteri's attorney says the case is a fistfight that's being blown out of proportion.
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Thursday, January 19, 2012
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I need to buy one of those portable oil heaters. A small one. Any recommends please? 
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A tamer Gervais leads predictable Golden Globes (AP)
BEVERLY HILLS, Calif. ? The Hollywood Foreign Press Association dared to let Ricky Gervais come back and host the Golden Globe Awards, a year after he insulted the organization and nearly everyone in the star-studded room with his lacerating wit.
But Gervais and the show seemed tamer and more predictable this year, not quite living up to outrageous reputations. Even the winners themselves, including "The Descendants" and its star, George Clooney, were predictable.
The victory for "The Descendants" in the best drama category sets it up in an expected battle at the Academy Awards with "The Artist," which won the award for best musical or comedy. Both had been frontrunners all along among people who are the business of prognosticating these things; Oscar nominations will be announced Jan. 24, with the ceremony itself coming Feb. 26.
Clooney won for his portrayal of a middle-aged husband struggling to raise his two daughters while their mother is in a coma. Jean Dujardin won the same award in the musical or comedy category for "The Artist" as a silent film actor whose career derails with the arrival of sound. ("The Artist" won the most film awards with three total, including one for Ludovic Bource's original score.)
It took the presenters and winners themselves to liven up the program ? and that includes Uggie, Dujardin's scene-stealing Jack Russell terrier in "The Artist," who performed some of his signature tricks on stage toward the end of the night.
While Gervais dropped an F-bomb a couple hours into the broadcast ? likely an accident after some imbibing on and offstage ? he also took aim at easy targets like Kim Kardashian. Later, wine glass in hand, he emerged from the wings to express delight in having "a job where you can get drunk and say what you want, and they still pay you."
After he introduced Madonna with a series of hackneyed puns about her song titles, including "Like a Virgin," the pop star shot back.
"If I'm still just like a virgin, Ricky, then why don't you come over here and do something about it?" she deadpanned. "I haven't kissed a girl in a few years ? on TV."
Male genitalia was a frequent theme. Tina Fey and Jane Lynch teamed up to make a penis pun inspired by "Hung" star Thomas Jane. Seth Rogen, taking the stage with the gorgeous Kate Beckinsale, cracked: "Hello, I'm Seth Rogen, and I'm currently trying to conceal a massive erection." And Clooney, in accepting his best-actor award, made a joke about fellow nominee Michael Fassbender, who plays a sex addict in "Shame."
"I'd like to thank Michael Fassbender for taking over the full-frontal nudity responsibility that I had," and Clooney then went on to suggest Fassbender could play golf with his hands behind his back.
Even Meryl Streep ? the grand dame of them all who won for best actress in a drama for her portrayal of former British Prime Minister Margaret Thatcher in "The Iron Lady" ? let an expletive slip during her acceptance speech. Streep got flustered when she realized she forgot her glasses at her table; instead she winged it, giving a rambling (but gracious) speech praising other actresses' performances, including some who hadn't even been nominated that night.
Two of Hollywood's most veteran and esteemed directors also were winners Sunday night, both of whom were venturing into 3-D for the first time: Martin Scorsese for best director for the family fantasy "Hugo" and Steven Spielberg for best animated film for "The Adventures of Tintin." Meanwhile, Woody Allen won for his screenplay for "Midnight in Paris" ? but naturally, he wasn't there to accept the statue in person. The comedy is his biggest hit in decades but he's typically reluctant to attend awards shows.
Things were much more fresh and inspired on the television side of the ceremony, with daring shows earning honors and longtime stars going home with statues for new roles.
"Homeland" on Showtime, which explores terrorism and an Iraq war veteran, earned awards for best drama and best actress in a drama for star Claire Danes. It was Danes' third Globe; she won her first when she was just 15 for "My So-Called Life."
Former "Frasier" star Kelsey Grammer won best actor in a drama for Starz's "Boss," while former "Friends" star Matt LeBlanc won best actor in a musical or comedy for Showtime's "Episodes."
ABC's "Modern Family" was the big winner among commercial broadcast networks, following up its Emmy for best television comedy by winning the Golden Globe. Creator Steve Levitan and actress Sofia Vergara accepted the award with a comic riff in which she spoke in Spanish and Levitan "translated."
Let's hope the after-parties got wilder.
___
AP Television Writer David Bauder contributed to this report.
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Wednesday, January 18, 2012
MRI Powered Pill-Sized Robot Swims Through Intestines
Having had to design surgical instruments to operate in in MRI imaging field (not just the magnetic field, but in the patient during a scan), I can answer this.
The warning on the machine is overly cautious. Almost any material can be put in in MRI, but should be tested. 99% would probably fail (and 99% of those can be predicted to fail). And who wants to test every friggin' thing someone wants to bring into an MRI room. Best just to say "NONE!"
But for stuff designed for the MRI, it's a different story.
There are 2 levels of compatibility: MRI safe and MRI compatible.
MRI safe means it won't hurt anyone. Don't use large pieces of ferro or paramagnetic materials, or the magnet will apply significant force. In other words, just don't use steel (plus a few other exotic alloys). And don't use long, thing wires, or you can create some induction heating from the radio waves (the R stands for resonance
MRI compatible means that the material won't disrupt the imaging field. Either by warping the magnetic field, messing with the radio waves, or creating discontinuities (the FFT algorithms create artifacts from abrupt hydrogen density changes. Air/interface is enough sometimes).
Turns out polymers are ideal, followed by ceramics. But a small group of diamagnetic metals work pretty well too (but still have dimension and geometry constraints). Gold, silver, lead, and copper work great. BeCu alloys can be used and replace steel.
A small item (20 mm x 5 mm dia) made of copper should be MRI safe. MRI compatible is something that has to be tested, but copper/polymer objects might not screw with the image too badly if designed well. And it makes great sense to tap the radio field for a little bit of power.
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A first: Brain support cells from umbilical cord stem cells
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Public release date: 17-Jan-2012[ | E-mail |
Share ] Contact: Barbara Abney
barb.abney@ucf.edu
407-823-5139
University of Central Florida
ORLANDO, Jan. 17, 2012 -- For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases.
"This is the first time this has been done with non-embryonic stem cells," says James Hickman, a University of Central Florida bioengineer and leader of the research group, whose accomplishment is described in the Jan. 18 issue of the journal ACS Chemical Neuroscience. http://pubs.acs.org/doi/abs/10.1021/cn200082q?prevSearch=Hickman&searchHistoryKey=
"We're very excited about where this could lead because it overcomes many of the obstacles present with embryonic stem cells."
Stem cells from umbilical cords do not pose an ethical dilemma because the cells come from a source that would otherwise be discarded. Another major benefit is that umbilical cells generally have not been found to cause immune reactions, which would simplify their potential use in medical treatments.
The pharmaceutical company Geron, based in Menlo Park, Calif., developed a treatment for spinal cord repair based on embryonic stem cells, but it took the company 18 months to get approval from the FDA for human trials due in large part to the ethical and public concerns tied to human embryonic stem cell research. This and other problems recently led to the company shutting down its embryonic stem cell division, highlighting the need for other alternatives.
Sensitive Cells
The main challenge in working with stem cells is figuring out the chemical or other triggers that will convince them to convert into a desired cell type. When the new paper's lead author, Hedvika Davis, a postdoctoral researcher in Hickman's lab, set out to transform umbilical stem cells into oligodendrocytes--critical structural cells that insulate nerves in the brain and spinal cord--she looked for clues from past research.
Davis learned that other research groups had found components on oligodendrocytes that bind with the hormone norephinephrine, suggesting the cells normally interact with this chemical and that it might be one of the factors that stimulates their production. So, she decided this would be a good starting point.
In early tests, she found that norepinephrine, along with other stem cell growth promoters, caused the umbilical stem cells to convert, or differentiate, into oligodendrocytes. However, that conversion only went so far. The cells grew but then stopped short of reaching a level similar to what's found in the human nervous system.
Davis decided that, in addition to chemistry, the physical environment might be critical.
To more closely approximate the physical restrictions cells face in the body, Davis set up a more confined, three-dimensional environment, growing cells on top of a microscope slide, but with a glass slide above them. Only after making this change, and while still providing the norephinphrine and other chemicals, would the cells fully mature into oligodendrocytes.
"We realized that the stem cells are very sensitive to environmental conditions," Davis said.
Medical Potential
This growth of oligodendrocytes, while crucial, is only a first step to potential medical treatments. There are two main options the group hopes to pursue through further research. The first is that the cells could be injected into the body at the point of a spinal cord injury to promote repair.
Another intriguing possibility for the Hickman team's work relates to multiple sclerosis and similar conditions. "Multiple sclerosis is one of the holy grails for this kind of research," said Hickman, whose group is collaborating with Stephen Lambert at UCF's medical school, another of the paper's authors, to explore biomedical possibilities.
Oligodendrocytes produce myelin, which insulates nerve cells, making it possible for them to conduct the electrical signals that guide movement and other functions. Loss of myelin leads to multiple sclerosis and other related conditions such as diabetic neuropathy.
The injection of new, healthy oligodendrocytes might improve the condition of patients suffering from such diseases. The teams are also hoping to develop the techniques needed to grow oligodendrocytes in the lab to use as a model system both for better understanding the loss and restoration of myelin and for testing potential new treatments.
"We want to do both," Hickman said. "We want to use a model system to understand what's going on and also to look for possible therapies to repair some of the damage, and we think there is great potential in both directions."
###
Besides Hickman and Davis, the other authors on the paper were Xiufang Guo, Stephen Lambert, and Maria Stancescu, all from the University of Central Florida.
UCF Stands For Opportunity --The University of Central Florida is a metropolitan research university that ranks as the second largest in the nation with more than 58,000 students. UCF's first classes were offered in 1968. The university offers impressive academic and research environments that power the region's economic development. UCF's culture of opportunity is driven by our diversity, Orlando environment, history of entrepreneurship and our youth, relevance and energy. For more information visit http://news.ucf.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 17-Jan-2012[ | E-mail |
Share ] Contact: Barbara Abney
barb.abney@ucf.edu
407-823-5139
University of Central Florida
ORLANDO, Jan. 17, 2012 -- For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases.
"This is the first time this has been done with non-embryonic stem cells," says James Hickman, a University of Central Florida bioengineer and leader of the research group, whose accomplishment is described in the Jan. 18 issue of the journal ACS Chemical Neuroscience. http://pubs.acs.org/doi/abs/10.1021/cn200082q?prevSearch=Hickman&searchHistoryKey=
"We're very excited about where this could lead because it overcomes many of the obstacles present with embryonic stem cells."
Stem cells from umbilical cords do not pose an ethical dilemma because the cells come from a source that would otherwise be discarded. Another major benefit is that umbilical cells generally have not been found to cause immune reactions, which would simplify their potential use in medical treatments.
The pharmaceutical company Geron, based in Menlo Park, Calif., developed a treatment for spinal cord repair based on embryonic stem cells, but it took the company 18 months to get approval from the FDA for human trials due in large part to the ethical and public concerns tied to human embryonic stem cell research. This and other problems recently led to the company shutting down its embryonic stem cell division, highlighting the need for other alternatives.
Sensitive Cells
The main challenge in working with stem cells is figuring out the chemical or other triggers that will convince them to convert into a desired cell type. When the new paper's lead author, Hedvika Davis, a postdoctoral researcher in Hickman's lab, set out to transform umbilical stem cells into oligodendrocytes--critical structural cells that insulate nerves in the brain and spinal cord--she looked for clues from past research.
Davis learned that other research groups had found components on oligodendrocytes that bind with the hormone norephinephrine, suggesting the cells normally interact with this chemical and that it might be one of the factors that stimulates their production. So, she decided this would be a good starting point.
In early tests, she found that norepinephrine, along with other stem cell growth promoters, caused the umbilical stem cells to convert, or differentiate, into oligodendrocytes. However, that conversion only went so far. The cells grew but then stopped short of reaching a level similar to what's found in the human nervous system.
Davis decided that, in addition to chemistry, the physical environment might be critical.
To more closely approximate the physical restrictions cells face in the body, Davis set up a more confined, three-dimensional environment, growing cells on top of a microscope slide, but with a glass slide above them. Only after making this change, and while still providing the norephinphrine and other chemicals, would the cells fully mature into oligodendrocytes.
"We realized that the stem cells are very sensitive to environmental conditions," Davis said.
Medical Potential
This growth of oligodendrocytes, while crucial, is only a first step to potential medical treatments. There are two main options the group hopes to pursue through further research. The first is that the cells could be injected into the body at the point of a spinal cord injury to promote repair.
Another intriguing possibility for the Hickman team's work relates to multiple sclerosis and similar conditions. "Multiple sclerosis is one of the holy grails for this kind of research," said Hickman, whose group is collaborating with Stephen Lambert at UCF's medical school, another of the paper's authors, to explore biomedical possibilities.
Oligodendrocytes produce myelin, which insulates nerve cells, making it possible for them to conduct the electrical signals that guide movement and other functions. Loss of myelin leads to multiple sclerosis and other related conditions such as diabetic neuropathy.
The injection of new, healthy oligodendrocytes might improve the condition of patients suffering from such diseases. The teams are also hoping to develop the techniques needed to grow oligodendrocytes in the lab to use as a model system both for better understanding the loss and restoration of myelin and for testing potential new treatments.
"We want to do both," Hickman said. "We want to use a model system to understand what's going on and also to look for possible therapies to repair some of the damage, and we think there is great potential in both directions."
###
Besides Hickman and Davis, the other authors on the paper were Xiufang Guo, Stephen Lambert, and Maria Stancescu, all from the University of Central Florida.
UCF Stands For Opportunity --The University of Central Florida is a metropolitan research university that ranks as the second largest in the nation with more than 58,000 students. UCF's first classes were offered in 1968. The university offers impressive academic and research environments that power the region's economic development. UCF's culture of opportunity is driven by our diversity, Orlando environment, history of entrepreneurship and our youth, relevance and energy. For more information visit http://news.ucf.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-01/uocf-afb011712.php
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Tuesday, January 17, 2012
T-Rob, Taylor lead No. 7 Kansas over No. 3 Baylor (AP)
LAWRENCE, Kan. ? Baylor sauntered into Allen Fieldhouse on Monday night with a No. 3 ranking, a perfect record and all the swagger that comes with the best start in school history.
The Bears left like so many other teams with designs on knocking the Jayhawks from their Big 12 perch: with a humbling defeat.
Thomas Robinson had 27 points and 14 rebounds, Tyshawn Taylor matched a career-high with 28 points and the seventh-ranked Jayhawks cruised to a 92-74 victory, proving once more that the road to a conference championship goes through Kansas.
"Start with their leadership. Thomas Robinson showed why he's a player of the year candidate. Tyshawn Taylor was outstanding," Baylor coach Scott Drew said. "Early on we didn't have some success in the paint, got away from it. From there we couldn't stop them all night long."
It was the first loss for Baylor in football or men's and women's basketball since Oct. 29 ? a span of 40 games. It also ruined the longest winning streak in school history.
"Their fans got into the game," said Perry Jones III, who had 18 points to lead Baylor. "We still tried to stay together and not let the noise affect us."
Quincy Miller added 17 points, Quincy Acy had 14 and Pierre Jackson had 11 points and 11 assists, but the long and lean Bears were dominated inside and had no answer for the combination of Robinson and Taylor, one of the best inside-outside tandems in the nation.
Robinson overpowered the Baylor front line with an array of rim-rattling dunks and short-range jumpers, while Taylor hit four 3-pointers and doled out six assists.
The outcome left No. 1 Syracuse and No. 12 Murray State as the only undefeated teams in Division I.
"If you let it affect you and affect you next game, you've got no chance," Drew said. "They did what they had to do. They defended the home court."
Travis Releford and Elijah Johnson added 11 points each for the Jayhawks (15-3, 5-0), who won their 16th straight game at Allen Fieldhouse and 10th in a row at home over the Bears.
Kansas is 17-2 against them all-time.
Facing its fourth top-10 opponent of the season, the veteran Jayhawks swarmed the younger Bears with pressure from the opening tip, making life miserable on both ends of the court.
Robinson provided the early boost, scoring eight of his 12 first-half points in the opening 6-plus minutes. The run included a dazzling one-handed dunk off an alley-oop feed from Taylor that set Twitter ablaze and generated a roar inside Allen Fieldhouse that could be heard in Kansas City.
"He pressed the up button and he went and got it," Taylor said with a grin.
The Bears answered the first salvo with a 16-5 run of their own.
Jones started it with a jumper, and Gary Franklin curled in a 3-pointer for his only points of the game. By the time Jackson knocked down another 3 and Acy added a basket inside, Baylor had pulled ahead 27-22 and Self asked for a timeout.
It sure seemed to settle down the Jayhawks.
Robinson scored on a nifty spin move inside and Jeff Withey added two free throws to start a 17-2 run to end the half. Taylor scored 11 of the final 13 points, including a 3 from the top of the key with Jackson staring him down in the closing seconds to make it 39-29.
"It's going to come down to the best players on each team making plays. That's what happened," Taylor said. "We came out in attack mode, and kept it on all game."
Jackson hit a 3-pointer to trim the lead to 39-32 in the opening minute of the second half, and Brady Heslip added another 3 a couple of minutes later to make it 43-37 with 17:32 to go.
That was as close as Baylor got.
Kansas scored on its next seven possessions, another dunk by Robinson pushing the lead to 59-42 with 13:04 left. The lead swelled to 19 when Taylor scored on an acrobatic scooping layup, missed the ensuing foul shot, and then hit a 3-pointer from the wing after Kansas got the offensive rebound.
Robinson's basket with 6:54 left made it a 20-point game.
"We missed some jump shots they got some run-outs, we didn't get back. They do such a good job in transition in this building," Drew said. "They feed off the atmosphere."
By the time Robinson checked out with just over a minute to go, the crowd that had jammed the Jayhawks' historic field house to the rafters ? and generated crowd noise registering at 114 decibels at the tip ? was on their feet and giving him a standing ovation.
It was the first time an unbeaten team had come to Kansas during Big 12 play. The last time it happened with a current league member was on Jan. 21, 1986, when Oklahoma came into the game 17-0.
Just like Baylor, the Sooners went home 17-1.
"Early on they were good, right now they're even better," Drew said, "and I think the nation saw how tough they are. But that's what's great about this league. Night in and night out, you're going to face good teams, and if you don't play well and they play well, you've got no chance."
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